Preheat your oven to 425°F (220°C) and line a baking sheet with parchment paper or a wire rack. This helps the skin crisp up.
Pat the drumsticks dry with paper towels. A dry surface helps the skin get crispy. Toss them with the olive oil, a pinch of salt, and a few grinds of black pepper.
Arrange the drumsticks on the rack or sheet in a single layer. Bake for 25 to 30 minutes, flipping halfway through, until the internal temperature reaches 165°F (74°C) and the skin is crisp.
Meanwhile, in a small bowl whisk together the hot sauce, melted butter, vinegar, garlic powder, and onion powder. Taste and adjust for heat or tang if you like it more or less spicy.
When the drumsticks are done, remove them from the oven and brush them generously with the buffalo glaze. Return to the oven for 5 minutes to set the glaze, then brush again for a glossy finish.
If you prefer extra crispiness, you can broil for 1–2 minutes at the end, watching closely to prevent burning.
Serve hot with celery sticks and ranch or blue cheese dressing on the side if you like. A cool dip helps balance the heat and adds a creamy contrast.