Bring a large pot of salted water to a boil, add the whole wheat penne pasta, and cook according to the package directions until al dente.
While the pasta cooks, heat the olive oil in a large skillet over medium heat and add the minced garlic.
Sauté the garlic for 1 to 2 minutes, stirring often, until fragrant but not browned, then remove the skillet from the heat and set aside.
Place the roasted red peppers, low-fat cottage cheese, plain Greek yogurt, grated Parmesan cheese, low-sodium vegetable broth, dried oregano, dried basil, smoked paprika, salt, and black pepper into a blender or food processor.
Blend the mixture on high until the sauce is completely smooth and creamy, scraping down the sides as needed.
Pour the blended roasted red pepper sauce into the skillet with the sautéed garlic and place the skillet back over low to medium-low heat.
Gently warm the sauce for 3 to 4 minutes, stirring often, until it is heated through but not boiling, then turn the heat to low.
When the pasta is al dente, reserve about 1/2 cup of the starchy cooking water, then drain the pasta well.
Add the drained pasta directly to the warm roasted red pepper sauce in the skillet and toss until every piece is well coated, adding a splash of the reserved pasta water if you want to loosen the sauce.
Taste the pasta and adjust the seasoning with a little more salt or black pepper if needed, then remove the skillet from the heat.
Sprinkle the chopped fresh parsley over the pasta, if using, and serve the high protein creamy roasted red pepper pasta hot.